Recombinant human CCL22/MDC, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW = 10.3 kDa (90aa).
Description
CCL22/MDC is a small cytokine belonging to the CC chemokine family. This protien displays chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. It interacts with cell surface chemokine receptors CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
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Trade Leads Directory -> All Trade Leads -> Chemicals -> Pharmaceutical Products -> Recombinant Human Chemokine (C-C Motif) Ligand 22, His-tagged
